Identification of Genetically Intact HIV-1 Proviruses in Specific CD4(+) T Cells from Effectively Treated Participants

Latent replication-competent HIV-1 persists in individuals on long-term antiretroviral therapy (ART). We developed the Full-Length Individual Proviral Sequencing (FLIPS) assay to determine the distribution of latent replication-competent HIV-1 within memory CD4(+) T cell subsets in six individuals o...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Hiener, Bonnie, Horsburgh, Bethany A., Eden, John-Sebastian, Barton, Kirston, Schlub, Timothy E., Lee, Eunok, von Stockenstrom, Susanne, Odevall, Lina, Milush, Jeffrey M., Liegler, Teri, Sinclair, Elizabeth, Hoh, Rebecca, Boritz, Eli A., Douek, Daniel, Fromentin, Rémi, Chomont, Nicolas, Deeks, Steven G., Hecht, Frederick M., Palmer, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960642/
https://ncbi.nlm.nih.gov/pubmed/29045846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.081
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