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Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites
Accumulating evidence suggests participation of RNA-binding proteins with intrinsically disordered domains (IDPs) in the DNA damage response (DDR). These IDPs form liquid compartments at DNA damage sites in a poly(ADP ribose) (PAR)-dependent manner. However, it is greatly unknown how the IDPs are in...
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| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7071921/ https://ncbi.nlm.nih.gov/pubmed/32094185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913280117 |
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