Genotoxicity of cisplatin and carboplatin in cultured human lymphocytes: a comparative study

Cisplatin and carboplatin are integral parts of many antineoplastic management regimens. Both platinum analogues are potent DNA alkylating agents that robustly induce genomic instability and promote apoptosis in tumor cells. Although the mechanism of action of both drugs is similar, cisplatin appear...

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Detalhes bibliográficos
Publicado no:Interdiscip Toxicol
Main Authors: AZAB, Belal, ALASSAF, Anood, ABU-HUMDAN, Abdulrahman, DARDAS, Zain, ALMOUSA, Hashem, ALSALEM, Mohammad, KHABOUR, Omar, HAMMAD, Hana, SALEH, Tareq, AWIDI, Abdalla
Formato: Artigo
Idioma:Inglês
Publicado em: Slovak Toxicology Society SETOX 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071837/
https://ncbi.nlm.nih.gov/pubmed/32206030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/intox-2019-0011
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