Genotoxicity of cisplatin and carboplatin in cultured human lymphocytes: a comparative study

Cisplatin and carboplatin are integral parts of many antineoplastic management regimens. Both platinum analogues are potent DNA alkylating agents that robustly induce genomic instability and promote apoptosis in tumor cells. Although the mechanism of action of both drugs is similar, cisplatin appear...

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Bibliografische gegevens
Gepubliceerd in:Interdiscip Toxicol
Hoofdauteurs: AZAB, Belal, ALASSAF, Anood, ABU-HUMDAN, Abdulrahman, DARDAS, Zain, ALMOUSA, Hashem, ALSALEM, Mohammad, KHABOUR, Omar, HAMMAD, Hana, SALEH, Tareq, AWIDI, Abdalla
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Slovak Toxicology Society SETOX 2019
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071837/
https://ncbi.nlm.nih.gov/pubmed/32206030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/intox-2019-0011
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