Genotoxicity of cisplatin and carboplatin in cultured human lymphocytes: a comparative study

Cisplatin and carboplatin are integral parts of many antineoplastic management regimens. Both platinum analogues are potent DNA alkylating agents that robustly induce genomic instability and promote apoptosis in tumor cells. Although the mechanism of action of both drugs is similar, cisplatin appear...

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Veröffentlicht in:Interdiscip Toxicol
Hauptverfasser: AZAB, Belal, ALASSAF, Anood, ABU-HUMDAN, Abdulrahman, DARDAS, Zain, ALMOUSA, Hashem, ALSALEM, Mohammad, KHABOUR, Omar, HAMMAD, Hana, SALEH, Tareq, AWIDI, Abdalla
Format: Artigo
Sprache:Inglês
Veröffentlicht: Slovak Toxicology Society SETOX 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071837/
https://ncbi.nlm.nih.gov/pubmed/32206030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/intox-2019-0011
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