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Genotoxicity of cisplatin and carboplatin in cultured human lymphocytes: a comparative study

Cisplatin and carboplatin are integral parts of many antineoplastic management regimens. Both platinum analogues are potent DNA alkylating agents that robustly induce genomic instability and promote apoptosis in tumor cells. Although the mechanism of action of both drugs is similar, cisplatin appear...

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Bibliografiska uppgifter
I publikationen:Interdiscip Toxicol
Huvudupphovsmän: AZAB, Belal, ALASSAF, Anood, ABU-HUMDAN, Abdulrahman, DARDAS, Zain, ALMOUSA, Hashem, ALSALEM, Mohammad, KHABOUR, Omar, HAMMAD, Hana, SALEH, Tareq, AWIDI, Abdalla
Materialtyp: Artigo
Språk:Inglês
Publicerad: Slovak Toxicology Society SETOX 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071837/
https://ncbi.nlm.nih.gov/pubmed/32206030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/intox-2019-0011
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