Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor

Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenetic profile of the Nanog gene, but whether chromatin organization actually plays a causal role in Nanog regulation is still unclear. Here, we report that...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: González-Rico, Francisco J., Vicente-García, Cristina, Fernández, Almudena, Muñoz-Santos, Diego, Montoliu, Lluís, Morales-Hernández, Antonio, Merino, Jaime M., Román, Angel-Carlos, Fernández-Salguero, Pedro M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071633/
https://ncbi.nlm.nih.gov/pubmed/32169107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00336-w
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