Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor

Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenetic profile of the Nanog gene, but whether chromatin organization actually plays a causal role in Nanog regulation is still unclear. Here, we report that...

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Bibliografiske detaljer
Udgivet i:Epigenetics Chromatin
Main Authors: González-Rico, Francisco J., Vicente-García, Cristina, Fernández, Almudena, Muñoz-Santos, Diego, Montoliu, Lluís, Morales-Hernández, Antonio, Merino, Jaime M., Román, Angel-Carlos, Fernández-Salguero, Pedro M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071633/
https://ncbi.nlm.nih.gov/pubmed/32169107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00336-w
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