Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor

Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenetic profile of the Nanog gene, but whether chromatin organization actually plays a causal role in Nanog regulation is still unclear. Here, we report that...

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Detaylı Bibliyografya
Yayımlandı:Epigenetics Chromatin
Asıl Yazarlar: González-Rico, Francisco J., Vicente-García, Cristina, Fernández, Almudena, Muñoz-Santos, Diego, Montoliu, Lluís, Morales-Hernández, Antonio, Merino, Jaime M., Román, Angel-Carlos, Fernández-Salguero, Pedro M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071633/
https://ncbi.nlm.nih.gov/pubmed/32169107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00336-w
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