Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor

Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenetic profile of the Nanog gene, but whether chromatin organization actually plays a causal role in Nanog regulation is still unclear. Here, we report that...

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Veröffentlicht in:Epigenetics Chromatin
Hauptverfasser: González-Rico, Francisco J., Vicente-García, Cristina, Fernández, Almudena, Muñoz-Santos, Diego, Montoliu, Lluís, Morales-Hernández, Antonio, Merino, Jaime M., Román, Angel-Carlos, Fernández-Salguero, Pedro M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071633/
https://ncbi.nlm.nih.gov/pubmed/32169107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00336-w
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