Tissue-specific characterization of mitochondrial branched-chain keto acid oxidation using a multiplexed assay platform

Alterations to branched-chain keto acid (BCKA) oxidation have been implicated in a wide variety of human diseases, ranging from diabetes to cancer. Although global shifts in BCKA metabolism—evident by gene transcription, metabolite profiling, and in vivo flux analyses have been documented across var...

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Publicado en:Biochem J
Autores principales: Goldberg, Emma J., Buddo, Katherine A., McLaughlin, Kelsey L., Fernandez, Regina F., Pereyra, Andrea S., Psaltis, Christine E., Lin, Chien-Te, Hagen, James T., Boykov, Ilya N., Nguyen, Tiffany K., Gowdy, Kymberly M., Ellis, Jessica M., Neufer, P. Darrell, McClung, Joseph M., Fisher-Wellman, Kelsey H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071349/
https://ncbi.nlm.nih.gov/pubmed/31092703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190182
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