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Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart.

The progeroid phenotype of mitochondrial DNA (mtDNA) mutator mice has been nebulously attributed to general mitochondrial “dysfunction”, though few studies have rigorously defined the bioenergetic consequences of accumulating mtDNA mutations. Comprehensive mitochondrial diagnostics was employed to i...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: McLaughlin, Kelsey L., McClung, Joseph M., Fisher-Wellman, Kelsey H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173612/
https://ncbi.nlm.nih.gov/pubmed/30217445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.09.022
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