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Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart.

The progeroid phenotype of mitochondrial DNA (mtDNA) mutator mice has been nebulously attributed to general mitochondrial “dysfunction”, though few studies have rigorously defined the bioenergetic consequences of accumulating mtDNA mutations. Comprehensive mitochondrial diagnostics was employed to i...

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Bibliografske podrobnosti
izdano v:Biochem Biophys Res Commun
Main Authors: McLaughlin, Kelsey L., McClung, Joseph M., Fisher-Wellman, Kelsey H.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173612/
https://ncbi.nlm.nih.gov/pubmed/30217445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.09.022
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