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Hydroxygenkwanin Suppresses Non-Small Cell Lung Cancer Progression by Enhancing EGFR Degradation

Epidermal growth factor receptor (EGFR) is frequently overexpressed and mutated in non-small cell lung cancer (NSCLC), which is the major type of lung cancer. The EGFR tyrosine kinase inhibitors (TKIs) are the approved treatment for patients harboring activating mutations in the EGFR kinase. However...

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Publicat a:Molecules
Autors principals: Leu, Yann-Lii, Wang, Tong-Hong, Wu, Chih-Ching, Huang, Kuo-Yen, Jiang, Yu-Wen, Hsu, Yi-Chiung, Chen, Chi-Yuan
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070862/
https://ncbi.nlm.nih.gov/pubmed/32093124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25040941
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