Hydroxygenkwanin Suppresses Non-Small Cell Lung Cancer Progression by Enhancing EGFR Degradation

Epidermal growth factor receptor (EGFR) is frequently overexpressed and mutated in non-small cell lung cancer (NSCLC), which is the major type of lung cancer. The EGFR tyrosine kinase inhibitors (TKIs) are the approved treatment for patients harboring activating mutations in the EGFR kinase. However...

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Detalhes bibliográficos
Main Authors: Yann-Lii Leu, Tong-Hong Wang, Chih-Ching Wu, Kuo-Yen Huang, Yu-Wen Jiang, Yi-Chiung Hsu, Chi-Yuan Chen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-02-01
Colecção:Molecules
Assuntos:
<i>daphne genkwa</i>
hydroxygenkwanin
nsclc
egfr
apoptosis
Acesso em linha:https://www.mdpi.com/1420-3049/25/4/941
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