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Hydroxygenkwanin Suppresses Non-Small Cell Lung Cancer Progression by Enhancing EGFR Degradation

Epidermal growth factor receptor (EGFR) is frequently overexpressed and mutated in non-small cell lung cancer (NSCLC), which is the major type of lung cancer. The EGFR tyrosine kinase inhibitors (TKIs) are the approved treatment for patients harboring activating mutations in the EGFR kinase. However...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Leu, Yann-Lii, Wang, Tong-Hong, Wu, Chih-Ching, Huang, Kuo-Yen, Jiang, Yu-Wen, Hsu, Yi-Chiung, Chen, Chi-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070862/
https://ncbi.nlm.nih.gov/pubmed/32093124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25040941
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