Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition

Alzheimer’s disease is the most common type of dementia, affecting millions of people worldwide. One of its main consequences is memory loss, which is related to downstream effectors of cyclic adenosine monophosphate (cAMP). A well-established strategy to avoid cAMP degradation is the inhibition of...

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Publicado en:Molecules
Main Authors: Cavalloro, Valeria, Russo, Katia, Vasile, Francesca, Pignataro, Luca, Torretta, Archimede, Donini, Stefano, Semrau, Marta S., Storici, Paola, Rossi, Daniela, Rapetti, Federica, Brullo, Chiara, Parisini, Emilio, Bruno, Olga, Collina, Simona
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070305/
https://ncbi.nlm.nih.gov/pubmed/32093112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25040935
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