Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment

The identification of novel pan-sigma receptor (SR) modulators, potentially useful in cancer treatment, represents a new goal of our research. Here, we report on the preparation of novel chiral compounds characterized by a 3-C alkyl chain bridging an aromatic portion to a 4-benzyl-piperidine moiety....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Marta Rui, Annamaria Marra, Vittorio Pace, Markus Juza, Daniela Rossi, Simona Collina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-09-01
Colecção:Molecules
Assuntos:
sigma receptor (SR) modulators
amylose- and cellulose-derived CSPs
chiral resolution
enantioselective HPLC
electronic circular dichroism (ECD)
Acesso em linha:http://www.mdpi.com/1420-3049/21/9/1210
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados