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Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment

The identification of novel pan-sigma receptor (SR) modulators, potentially useful in cancer treatment, represents a new goal of our research. Here, we report on the preparation of novel chiral compounds characterized by a 3-C alkyl chain bridging an aromatic portion to a 4-benzyl-piperidine moiety....

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Rui, Marta, Marra, Annamaria, Pace, Vittorio, Juza, Markus, Rossi, Daniela, Collina, Simona
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273946/
https://ncbi.nlm.nih.gov/pubmed/27626396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21091210
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