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Angiotensin‐(1‐7) mitigated angiotensin II‐induced abdominal aortic aneurysms in apolipoprotein E‐knockout mice

BACKGROUND AND PURPOSE: To test the hypothesis that angiotensin‐(1‐7) [Ang‐(1‐7)] may attenuate abdominal aortic aneurysm (AAA) via inhibiting vascular inflammation, extracellular matrix degradation, and smooth muscle cell (SMC) apoptosis, an animal model of AAA was established by angiotensin II (An...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Xue, Fei, Yang, Jianmin, Cheng, Jing, Sui, Wenhai, Cheng, Cheng, Li, Hongxuan, Zhang, Meng, Zhang, Jie, Xu, Xingli, Ma, Jing, Lu, Lin, Xu, Jinfeng, Zhang, Yun, Zhang, Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070176/
https://ncbi.nlm.nih.gov/pubmed/31658493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14906
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