Melatonin attenuates angiotensin II-induced abdominal aortic aneurysm through the down-regulation of matrix metalloproteinases

Abdominal aortic aneurysm (AAA) affects more than 5% of the population in developed countries and the pharmacotherapies for AAA are limited. Here, we explored whether melatonin regulates the development of AAA. In smooth muscle cells, melatonin treatment decreases angiotensin II-induced matrix metal...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Kong, Jing, Zhang, Ya, Liu, Shanshan, Li, Hongxuan, Liu, Shangming, Wang, Jingjing, Qin, Xiaoteng, Jiang, Xiuxin, Yang, Jianmin, Zhang, Cheng, Zhang, Wencheng
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper: Pathology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362405/
https://ncbi.nlm.nih.gov/pubmed/28179581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15093
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