Melatonin attenuates angiotensin II-induced abdominal aortic aneurysm through the down-regulation of matrix metalloproteinases

Abdominal aortic aneurysm (AAA) affects more than 5% of the population in developed countries and the pharmacotherapies for AAA are limited. Here, we explored whether melatonin regulates the development of AAA. In smooth muscle cells, melatonin treatment decreases angiotensin II-induced matrix metal...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Kong, Jing, Zhang, Ya, Liu, Shanshan, Li, Hongxuan, Liu, Shangming, Wang, Jingjing, Qin, Xiaoteng, Jiang, Xiuxin, Yang, Jianmin, Zhang, Cheng, Zhang, Wencheng
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
Предметы:
Research Paper: Pathology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362405/
https://ncbi.nlm.nih.gov/pubmed/28179581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15093
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