Smooth muscle-specific Gsα deletion exaggerates angiotensin II-induced abdominal aortic aneurysm formation in mice in vivo

OBJECTIVE: Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease without an effective pharmaceutical treatment. Genetic studies have proved the involvement of smooth muscle phenotype switch in the development of AAA. The alpha subunit of the heterotrimeric G stimulatory protein (Gsα...

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Publicat a:J Mol Cell Cardiol
Autors principals: Qin, Xiaoteng, He, Lifan, Tian, Mi, Hu, Ping, Yang, Jianmin, Lu, Huixia, Chen, Wenqiang, Jiang, Xiuxin, Zhang, Cheng, Gao, Jiangang, Chen, Min, Weinstein, Lee S., Zhang, Yun, Zhang, Wencheng
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394040/
https://ncbi.nlm.nih.gov/pubmed/31071332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2019.05.002
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