UCP-2 is involved in angiotensin-II-induced abdominal aortic aneurysm in apolipoprotein E-knockout mice

UCP-2 shows an important role in modulating of mitochondrial membrane potential and cell apoptosis. Whether or not UCP-2 could been a critical factor in preventing AAA formation is not known. We report that UCP-2 protein and mRNA expression were significantly higher in Ang-Ⅱ-induced AAA of mice. The...

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Bibliographic Details
Published in:PLoS One
Main Authors: Yan, Peng, Chen, Ken, Wang, Qiang, Yang, Dachun, Li, De, Yang, Yongjian
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500278/
https://ncbi.nlm.nih.gov/pubmed/28683125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179743
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