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Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice

AIMS: Abdominal aortic aneurysm (AAA) is characterized by extensive aortic wall matrix degradation that contributes to the remodelling and eventual rupture of the arterial wall. Elastinolytic cathepsin S (Cat S) is highly expressed in human aneurysmal lesions, but whether it contributes to the patho...

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Hlavní autoři: Qin, Yanwen, Cao, Xu, Guo, Jun, Zhang, Yaozhong, Pan, Lili, Zhang, Hongjia, Li, Huihua, Tang, Chaoshu, Du, Jie, Shi, Guo-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500043/
https://ncbi.nlm.nih.gov/pubmed/22871592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs263
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