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Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest

Cancer is a life-threatening disease that affects one in three people. Although most cases are sporadic, cancer risk can be increased by genetic factors. It remains unknown why certain genes predispose for specific forms of cancer only, such as checkpoint protein 2 (CHK2), in which gene mutations co...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogenesis
Prif Awduron: van Jaarsveld, Marijn T. M., Deng, Difan, Ordoñez-Rueda, Diana, Paulsen, Malte, Wiemer, Erik A. C., Zi, Zhike
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070093/
https://ncbi.nlm.nih.gov/pubmed/32170104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-0219-y
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