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Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest

Cancer is a life-threatening disease that affects one in three people. Although most cases are sporadic, cancer risk can be increased by genetic factors. It remains unknown why certain genes predispose for specific forms of cancer only, such as checkpoint protein 2 (CHK2), in which gene mutations co...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: van Jaarsveld, Marijn T. M., Deng, Difan, Ordoñez-Rueda, Diana, Paulsen, Malte, Wiemer, Erik A. C., Zi, Zhike
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070093/
https://ncbi.nlm.nih.gov/pubmed/32170104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-0219-y
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