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The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition
The Aurora B abscission checkpoint delays cytokinesis until resolution of DNA trapped in the cleavage furrow. This process involves PKCε phosphorylation of Aurora B S227. Assessing if this PKCε-Aurora B module provides a more widely exploited genome-protective control for the cell cycle, we show Aur...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7070073/ https://ncbi.nlm.nih.gov/pubmed/32170202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15163-6 |
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