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Cholesteryl α-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium

Helicobacter pylori, the most common etiologic agent of gastric diseases including gastric cancer, is auxotrophic for cholesterol and has to hijack it from gastric epithelia. Upon uptake, the bacteria convert cholesterol to cholesteryl 6′-O-acyl-α-D-glucopyranoside (CAG) to promote lipid raft cluste...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Jan, Hau-Ming, Chen, Yi-Chi, Yang, Tsai-Chen, Ong, Lih-Lih, Chang, Chia-Chen, Muthusamy, Sasikala, Abera, Andualem Bahiru, Wu, Ming-Shiang, Gervay-Hague, Jacquelyn, Mong, Kwok-Kong Tony, Lin, Chun-Hung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069968/
https://ncbi.nlm.nih.gov/pubmed/32170208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0855-y
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