Cholesteryl α-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium

Helicobacter pylori, the most common etiologic agent of gastric diseases including gastric cancer, is auxotrophic for cholesterol and has to hijack it from gastric epithelia. Upon uptake, the bacteria convert cholesterol to cholesteryl 6′-O-acyl-α-D-glucopyranoside (CAG) to promote lipid raft cluste...

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Udgivet i:Commun Biol
Main Authors: Jan, Hau-Ming, Chen, Yi-Chi, Yang, Tsai-Chen, Ong, Lih-Lih, Chang, Chia-Chen, Muthusamy, Sasikala, Abera, Andualem Bahiru, Wu, Ming-Shiang, Gervay-Hague, Jacquelyn, Mong, Kwok-Kong Tony, Lin, Chun-Hung
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069968/
https://ncbi.nlm.nih.gov/pubmed/32170208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0855-y
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