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Divergent behavioral responses in protracted opioid withdrawal in male and female C57BL/6J mice

Persons suffering from opioid use disorder (OUD) experience long-lasting dysphoric symptoms well into extended periods of withdrawal. This protracted withdrawal syndrome is notably characterized by heightened anxiety and hyperkatifeia. Here we investigated if an exacerbated withdrawal model of acute...

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Publicat a:Eur J Neurosci
Autors principals: Bravo, Isabel M., Luster, Brennon R., Flanigan, Meghan E., Perez, Patric J., Cogan, Elizabeth S., Schmidt, Karl T., McElligott, Zoe A.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069788/
https://ncbi.nlm.nih.gov/pubmed/31544297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14580
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