Divergent behavioral responses in protracted opioid withdrawal in male and female C57BL/6J mice

Persons suffering from opioid use disorder (OUD) experience long-lasting dysphoric symptoms well into extended periods of withdrawal. This protracted withdrawal syndrome is notably characterized by heightened anxiety and hyperkatifeia. Here we investigated if an exacerbated withdrawal model of acute...

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Veröffentlicht in:Eur J Neurosci
Hauptverfasser: Bravo, Isabel M., Luster, Brennon R., Flanigan, Meghan E., Perez, Patric J., Cogan, Elizabeth S., Schmidt, Karl T., McElligott, Zoe A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069788/
https://ncbi.nlm.nih.gov/pubmed/31544297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14580
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