Resolvin D1 Modulates the Intracellular VEGF-Related miRNAs of Retinal Photoreceptors Challenged With High Glucose

Stimulation of retinal photoreceptors with elevated glucose concentration (30 mM) for 96 h, served as diabetic retinopathy in vitro model to study Resolvin D1 (50 nM) effects on neovascularization. VEGF and anti-angiogenic miR-20a-3p, miR-20a-5p, miR-106a-5p, and miR-20b expression was assessed eith...

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Опубликовано в: :Front Pharmacol
Главные авторы: Maisto, Rosa, Trotta, Maria Consiglia, Petrillo, Francesco, Izzo, Sara, Cuomo, Giovanna, Alfano, Roberto, Hermenean, Anca, Barcia, Jorge Miquel, Galdiero, Marilena, Platania, Chiara Bianca Maria, Bucolo, Claudio, D’Amico, Michele
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069219/
https://ncbi.nlm.nih.gov/pubmed/32210819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00235
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