Resolvin D1 Modulates the Intracellular VEGF-Related miRNAs of Retinal Photoreceptors Challenged With High Glucose

Stimulation of retinal photoreceptors with elevated glucose concentration (30 mM) for 96 h, served as diabetic retinopathy in vitro model to study Resolvin D1 (50 nM) effects on neovascularization. VEGF and anti-angiogenic miR-20a-3p, miR-20a-5p, miR-106a-5p, and miR-20b expression was assessed eith...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Maisto, Rosa, Trotta, Maria Consiglia, Petrillo, Francesco, Izzo, Sara, Cuomo, Giovanna, Alfano, Roberto, Hermenean, Anca, Barcia, Jorge Miquel, Galdiero, Marilena, Platania, Chiara Bianca Maria, Bucolo, Claudio, D’Amico, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069219/
https://ncbi.nlm.nih.gov/pubmed/32210819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00235
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