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Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa

Although an increasing number of disease genes have been identified, the exact cellular mechanisms of retinitis pigmentosa (RP) remain largely unclear. Retinal organoids (ROs) derived from the induced pluripotent stem cells (iPSCs) of patients provide a potential but unvalidated platform for deciphe...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Gao, Mei-Ling, Lei, Xin-Lan, Han, Fang, He, Kai-Wen, Jin, Si-Qian, Zhang, You-You, Jin, Zi-Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068133/
https://ncbi.nlm.nih.gov/pubmed/32211407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00128
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