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Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa

Although an increasing number of disease genes have been identified, the exact cellular mechanisms of retinitis pigmentosa (RP) remain largely unclear. Retinal organoids (ROs) derived from the induced pluripotent stem cells (iPSCs) of patients provide a potential but unvalidated platform for deciphe...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Gao, Mei-Ling, Lei, Xin-Lan, Han, Fang, He, Kai-Wen, Jin, Si-Qian, Zhang, You-You, Jin, Zi-Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068133/
https://ncbi.nlm.nih.gov/pubmed/32211407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00128
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