Phase I Pharmacokinetic Study of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in Healthy Adult and Adolescent Populations

INTRODUCTION: A fixed-dose combination (FDC) of ibuprofen and acetaminophen has been developed that provides greater analgesic efficacy than either agent alone at the same doses without increasing the risk for adverse events. METHODS: We report three clinical phase I studies designed to assess the p...

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Опубликовано в: :Drugs R D
Главные авторы: Tarabar, Sanela, Kelsh, Debra, Vince, Bradley, Leyva, Rina, Song, Dongweon, Matschke, Kyle, Kellstein, David E., Meeves, Suzanne, Cruz-Rivera, Mario
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2020
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Original Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067710/
https://ncbi.nlm.nih.gov/pubmed/32130679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-020-00293-5
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