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Phase I Pharmacokinetic Study of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in Healthy Adult and Adolescent Populations

INTRODUCTION: A fixed-dose combination (FDC) of ibuprofen and acetaminophen has been developed that provides greater analgesic efficacy than either agent alone at the same doses without increasing the risk for adverse events. METHODS: We report three clinical phase I studies designed to assess the p...

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Detalhes bibliográficos
Publicado no:Drugs R D
Main Authors: Tarabar, Sanela, Kelsh, Debra, Vince, Bradley, Leyva, Rina, Song, Dongweon, Matschke, Kyle, Kellstein, David E., Meeves, Suzanne, Cruz-Rivera, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067710/
https://ncbi.nlm.nih.gov/pubmed/32130679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-020-00293-5
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