Phase I Pharmacokinetic Study of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in Healthy Adult and Adolescent Populations

INTRODUCTION: A fixed-dose combination (FDC) of ibuprofen and acetaminophen has been developed that provides greater analgesic efficacy than either agent alone at the same doses without increasing the risk for adverse events. METHODS: We report three clinical phase I studies designed to assess the p...

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Bibliografiske detaljer
Udgivet i:Drugs R D
Main Authors: Tarabar, Sanela, Kelsh, Debra, Vince, Bradley, Leyva, Rina, Song, Dongweon, Matschke, Kyle, Kellstein, David E., Meeves, Suzanne, Cruz-Rivera, Mario
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067710/
https://ncbi.nlm.nih.gov/pubmed/32130679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-020-00293-5
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