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Disrupting insulin signaling in Schwann cells impairs myelination and induces a sensory neuropathy

Although diabetic mice have been studied for decades, little is known about the cell type specific contributions to diabetic neuropathy (DN). Schwann cells (SCs) myelinate and provide trophic support to peripheral nervous system axons. Altered SC metabolism leads to myelin defects, which can be seen...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Hackett, Amber R., Strickland, Amy, Milbrandt, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067678/
https://ncbi.nlm.nih.gov/pubmed/31758725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23755
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