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Disrupting insulin signaling in Schwann cells impairs myelination and induces a sensory neuropathy

Although diabetic mice have been studied for decades, little is known about the cell type specific contributions to diabetic neuropathy (DN). Schwann cells (SCs) myelinate and provide trophic support to peripheral nervous system axons. Altered SC metabolism leads to myelin defects, which can be seen...

詳細記述

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書誌詳細
出版年:Glia
主要な著者: Hackett, Amber R., Strickland, Amy, Milbrandt, Jeffrey
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067678/
https://ncbi.nlm.nih.gov/pubmed/31758725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23755
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