FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair

Vertebrate DNA crosslink repair excises toxic replication-blocking DNA crosslinks. Numerous factors involved in crosslink repair have been identified, and mutations in their corresponding genes cause Fanconi anemia (FA). A key step in crosslink repair is monoubiquitination of the FANCD2–FANCI hetero...

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Gepubliceerd in:Nat Struct Mol Biol
Hoofdauteurs: Alcón, Pablo, Shakeel, Shabih, Chen, Zhuo A., Rappsilber, Juri, Patel, Ketan J., Passmore, Lori A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067600/
https://ncbi.nlm.nih.gov/pubmed/32066963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0380-1
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