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Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia

Since hypobaric hypoxia significantly affects metabolic characteristics of intestinal flora, which plays an important role in the biotransformation of aspirin, high altitudes may influence the pharmacokinetics and therapeutic effects of aspirin in the intestines. In the present study, to test altera...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sun, Yuemei, Zhang, Juanhong, Zhao, Anpeng, Li, Wenbin, Feng, Qiangsheng, Wang, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067402/
https://ncbi.nlm.nih.gov/pubmed/32163488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230197
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