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Plateau hypoxia attenuates the metabolic activity of intestinal flora to enhance the bioavailability of nifedipine
Nifedipine is completely absorbed by the gastrointestinal tract and its pharmacokinetics and metabolism may be influenced by microorganisms. If gut microbes are involved in the metabolism of nifedipine, plateau hypoxia may regulate the bioavailability and the therapeutic effect of nifedipine by alte...
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| Publicado no: | Drug Deliv |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6058681/ https://ncbi.nlm.nih.gov/pubmed/29790376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1469687 |
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