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Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia

Since hypobaric hypoxia significantly affects metabolic characteristics of intestinal flora, which plays an important role in the biotransformation of aspirin, high altitudes may influence the pharmacokinetics and therapeutic effects of aspirin in the intestines. In the present study, to test altera...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Sun, Yuemei, Zhang, Juanhong, Zhao, Anpeng, Li, Wenbin, Feng, Qiangsheng, Wang, Rong
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067402/
https://ncbi.nlm.nih.gov/pubmed/32163488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230197
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