Intracellular Neutralization of Ricin Toxin by Single Domain Antibodies Targeting the Active Site

The extreme potency of the plant toxin, ricin, is due to its enzymatic subunit, RTA, which inactivates mammalian ribosomes with near perfect efficiency. Here we characterized, at the functional and structural levels, seven alpaca single-domain antibodies (V(H)Hs) previously reported to recognize epi...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Mol Biol
Hoofdauteurs: Rudolph, Michael J., Czajka, Timothy F., Davis, Simon A., Nguyen, Chi My Thi, Li, Xiao-ping, Tumer, Nilgun E., Vance, David J., Mantis, Nicholas J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066583/
https://ncbi.nlm.nih.gov/pubmed/31931008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.01.006
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items