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Formulation and Intracellular Trafficking of Lipid–Drug Conjugate Nanoparticles Containing a Hydrophilic Antitubercular Drug for Improved Intracellular Delivery to Human Macrophages

[Image: see text] Isoniazid is an important first-line antitubercular drug used in the treatment of all major clinical manifestations of tuberculosis, including both pulmonary and cerebral diseases. However, it is associated with significant drawbacks due to its inherent hydrophilic nature, includin...

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Détails bibliographiques
Publié dans:ACS Omega
Auteurs principaux: Pandit, Sayantan, Roy, Subhadeep, Pillai, Jonathan, Banerjee, Subham
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2020
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066568/
https://ncbi.nlm.nih.gov/pubmed/32175491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03523
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