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Formulation and Intracellular Trafficking of Lipid–Drug Conjugate Nanoparticles Containing a Hydrophilic Antitubercular Drug for Improved Intracellular Delivery to Human Macrophages

[Image: see text] Isoniazid is an important first-line antitubercular drug used in the treatment of all major clinical manifestations of tuberculosis, including both pulmonary and cerebral diseases. However, it is associated with significant drawbacks due to its inherent hydrophilic nature, includin...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Pandit, Sayantan, Roy, Subhadeep, Pillai, Jonathan, Banerjee, Subham
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066568/
https://ncbi.nlm.nih.gov/pubmed/32175491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03523
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