Loading...

Chemical modification of melphalan as a key to improving treatment of haematological malignancies

Chemical modification of known, effective drugs is one method to improve chemotherapy. Thus, the object of this study was to generate melphalan derivatives with improved cytotoxic activity in human cancer cells (RPMI8226, HL60 and THP1). Several melphalan derivatives were synthesised, modified in th...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Gajek, Arkadiusz, Poczta, Anastazja, Łukawska, Małgorzata, Cecuda- Adamczewska, Violetta, Tobiasz, Joanna, Marczak, Agnieszka
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066245/
https://ncbi.nlm.nih.gov/pubmed/32161295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61436-x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!