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Novel oxazolinoanthracyclines as tumor cell growth inhibitors—Contribution of autophagy and apoptosis in solid tumor cells death

Chemical modification of known, effective drugs are one method to improve the chemotherapy of tumors. We reported ability of oxazoline analogs of doxorubicin (O-DOX) and daunorubicin (O-DAU) to induce apoptosis and autophagy in ovarian and liver cancer cells. Reactive oxygen and nitrogen species (RO...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Rogalska, Aneta, Gajek, Arkadiusz, Łukawska, Małgorzata, Oszczapowicz, Irena, Marczak, Agnieszka
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057680/
https://ncbi.nlm.nih.gov/pubmed/30040861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201296
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