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Novel oxazolinoanthracyclines as tumor cell growth inhibitors—Contribution of autophagy and apoptosis in solid tumor cells death

Chemical modification of known, effective drugs are one method to improve the chemotherapy of tumors. We reported ability of oxazoline analogs of doxorubicin (O-DOX) and daunorubicin (O-DAU) to induce apoptosis and autophagy in ovarian and liver cancer cells. Reactive oxygen and nitrogen species (RO...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rogalska, Aneta, Gajek, Arkadiusz, Łukawska, Małgorzata, Oszczapowicz, Irena, Marczak, Agnieszka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057680/
https://ncbi.nlm.nih.gov/pubmed/30040861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201296
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