Therapeutic intervention in relapsing autoimmune demyelinating disease through induction of myelin-specific regulatory CD8 T cell responses

Multiple Sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS). We have shown that CNS-specific CD8 T cells (CNS-CD8) possess a disease suppressive function in MS and its animal model, experimental autoimmune encephalomyelitis (EAE). Previous studies have focused...

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Detalhes bibliográficos
Publicado no:J Transl Autoimmun
Main Authors: Brate, Ashley A., Boyden, Alexander W., Itani, Farah R., Pewe, Lecia L., Harty, John T., Karandikar, Nitin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065686/
https://ncbi.nlm.nih.gov/pubmed/32161909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtauto.2019.100010
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