CD8(+) T Cells Are Required For Glatiramer Acetate Therapy in Autoimmune Demyelinating Disease

The exact mechanism of glatiramer acetate (GA, Copaxone®), an FDA-approved immunomodulatory therapy for multiple sclerosis (MS), remains unclear after decades of research. Previously, we have shown that GA therapy of MS induces CD8(+) T cell responses that can potentially suppress pathogenic CD4(+)...

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Hauptverfasser: Tyler, Andrew F., Mendoza, Jason P., Firan, Mihail, Karandikar, Nitin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689655/
https://ncbi.nlm.nih.gov/pubmed/23805274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066772
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