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Immune autoregulatory CD8 T cells require IFNγ responsiveness to optimally suppress CNS autoimmunity

Investigating the complex cellular interplay controlling immunopathogenic and immunoregulatory responses is critical for understanding multiple sclerosis (MS) and for developing successful immunotherapies. Our group has demonstrated that central nervous system (CNS) myelin-specific CD8 T cells unexp...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Boyden, Alexander W., Brate, Ashley A., Stephens, Laura M., Karandikar, Nitin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343581/
https://ncbi.nlm.nih.gov/pubmed/32532836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000211
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